Description

This entry-level textbook, covering the area of tissue optics, is based on the lecture notes for a graduate course (Bio-optical Imaging) that has been taught six times by the authors at Texas A&M University. After the fundamentals of photon transport in biological tissues are established, various optical imaging techniques for biological tissues will be covered. The imaging modalities will include ballistic imaging, quasi-ballistic imaging (optical coherence tomography), diffusion imaging, and ultrasound-aided hybrid imaging. The basic physics and engineering of each imaging technique will be emphasized.

 

Table of Contents

1. INTRODUCTION.

1.1.Motivation for optical imaging.

1.2.General behavior of light in biological tissue.

1.3.Basic physics of light-matter interaction.

1.4.Absorption and its biological origins.

1.5.Scattering and its biological origins.

1.6.Polarization and its biological origins.

1.7.Fluorescence and its biological origins.

1.8.Image characterization.

1.9.References.

1.10.Further readings.

1.11.Problems.

2. RAYLEIGH THEORY AND MIE THEORY FOR A SINGLE SCATTERER.

2.1.Introduction.

2.2.Summary of the Rayleigh theory.

2.3.Numerical example of the Rayleigh theory.

2.4.Summary of the Mie theory.

2.5.Numerical example of the Mie theory.

2.6.Appendix 2.A. Derivation of the Rayleigh theory.

2.7.Appendix 2.B. Derivation of the Mie theory.

2.8.References.

2.9.Further readings.

2.10.Problems.

3. MONTE CARLO MODELING OF PHOTON TRANSPORT IN BIOLOGICAL TISSUE.

3.1.Introduction.

3.2.Monte Carlo method.

3.3.Definition of problem.

3.4.Propagation of photons.

3.5.Physical quantities.

3.6.Computational examples.

3.7.Appendix 3.A. Summary of MCML.

3.8.Appendix 3.B. Probability density function.

3.9.References.

3.10.Further readings.

3.11.Problems.

4. CONVOLUTION FOR BROAD-BEAM RESPONSES.

4.1.Introduction.

4.2.General formulation of convolution.

4.3.Convolution over a Gaussian beam.

4.4.Convolution over a top-hat beam.

4.5.Numerical solution to convolution. <