Neuroscience has become a buzz-word in contempory lives. The neuroscience research came in a big way when Roger Sperry received Noble Prize for his split-brain research. Since mid-eighties, Neuroscience has expanded new possibilities, highlighted unexplored areas of knowledge and has provided connectivity amongst many fields. New topics have been identified, novel concerns have been expressed and many solutions have been generated. In the context of leadership research, this New Look Approach has opened new frontiers of knowledge. A number of issues in leadership that remained unexplainable in the past are now examined through neuroscientific lenses. The initial explorations have generated optimistic outcomes. Since neuroscientific investigation is relatively a new entry into our leadership arena, the furthering of such efforts is likely to yield promising dividends.