* An updated version of the original guide, providing an improved understanding of the many fundamental aspects of the electrospray process * Addresses latest developments including the emergence of new fields such as proteomics and metabolomics, that have flourished largely through the use of electrospray mass spectrometry * Includes a new section of the analytical aspects of electrospray with chapters on chromatographic coupling and quantitation; probing noncovalent interactions; and collision induced dissociation of even electrons