Since childhood, Nila Carter was made to spend every weekend at the family cabin. In her teenage years she believed it to be a prison. As an adult it became her sanctuary and means to survive. When a mysterious outbreak occurs in India, Nila's brother, Bobby, a virologist with the CDC, places the family on a precautionary alert to be ready to bug out. Unlike anything he's ever seen, the rabieslike virus is not only deadly but causes extreme violent behavior in anyone who becomes infected. Following her brother's advice, Nila begins to stockpile.After months of preparing, just as it seems the virus is over, everything implodes and Bobby informs them to leave the city. With her family, Nila heads to the mountains and to her father's isolated cabin. There she is eventually joined by friends and strangers, all hoping to safely stay clear of the virus that grips the world. While there, the group forms a tight bond, feeling secure that they will beat the extinction event and in due course return home. As time moves on, Nila quickly learns there are things they cannot run from.