Horace, Morris, and Dolores do everything together and know that they will be Friends Forever...until one day, when Horace and Morris become part of an exclusive boys' club and Dolores finds herself left out. Soon, she, too, finds her own club, where no boys are allowed and girls are supposed to have fun doing girl stuff. But after a while, Horace and Morris and Dolores realize they aren't happy at all doing what everyone in their clubs seems to enjoy. They miss each other. Is it too late to be friends again? Join these three charming mouse friends as they learn to do what they like, rather than what others say they should like.

何瑞斯、莫里斯和朵洛莉絲無論做什麼事情都會一起，他們都認為彼此是永遠的好朋友。直到有一天，何瑞斯和莫里斯加入了一個男生專屬的小團體，朵洛莉絲覺得自己被孤立了，於是她也加入了另一個小團體。她的小團體只玩女生的遊戲，不歡迎任何男生。但是不久之後，當其他人快樂的玩耍時，他們三個發現自己一點都不覺得開心，因為他們很想念彼此。難道他們再也不能做好朋友了嗎？來看看三隻可愛的小老鼠如何學習選擇自己所愛，而不是讓別人告訴他們應該喜歡什麼。